The Ischemic Stroke Genetics Study (ISGS) Protocol
نویسندگان
چکیده
منابع مشابه
The Ischemic Stroke Genetics Study (ISGS) Protocol
BACKGROUND The molecular basis for the genetic risk of ischemic stroke is likely to be multigenic and influenced by environmental factors. Several small case-control studies have suggested associations between ischemic stroke and polymorphisms of genes that code for coagulation cascade proteins and platelet receptors. Our aim is to investigate potential associations between hemostatic gene poly...
متن کاملThe Genetics of Ischemic Stroke
Pankaj Sharma is Professor of Neurology at Royal Holloway University of London and Director of its Institute of Cardiovascular Research (ICR2UL) which is closely partnered with local hospitals Ashford & St Peters NHS Foundation Trust. PS is also consultant neurologist at Imperial College London, Editor-in-Chief of the Journal of the Royal Society of Medicine Cardiovascular Disease and Hon. Medi...
متن کاملGenetics of ischemic stroke.
Stroke is the third leading cause of death and a major cause of disability worldwide. Most cases of ischemic stroke are attributable to hypertension and other risk factors, but in over 20% of cases, the cause is unknown. Recent research has implicated some novel genes in the etiology of ischemic stroke, including genes for soluble epoxide hydrolase (sHE), 5-lipoxygenase activating protein (FLAP...
متن کاملPathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network.
BACKGROUND AND PURPOSE NINDS (National Institute of Neurological Disorders and Stroke)-SiGN (Stroke Genetics Network) is an international consortium of ischemic stroke studies that aims to generate high-quality phenotype data to identify the genetic basis of pathogenic stroke subtypes. This analysis characterizes the etiopathogenetic basis of ischemic stroke and reliability of stroke classifica...
متن کاملSex differences in stroke evaluations in the Ischemic Stroke Genetics Study.
BACKGROUND Epidemiologic studies suggest sex differences in evaluation of patients presenting with ischemic stroke. Sex differences in stroke evaluation could lead to sex differences in the validity of diagnosing ischemic stroke subtypes. This study assessed sex differences in the Ischemic Stroke Genetics Study (ISGS). METHODS The ISGS is a prospective case-control genetic association study o...
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ژورنال
عنوان ژورنال: BMC Neurology
سال: 2003
ISSN: 1471-2377
DOI: 10.1186/1471-2377-3-4